Plataforma de Información Curricular

Research Interest

Influence of the neuroimmunoendocrine context on prostate physiopathology

Most Recent Publications

1. Anguiano B (autor responsable), Montes de Oca C, Delgado-González E, Aceves C. , Prostate Gland a Target Organ of Thyroid Hormones Action; Advances and Controversies. , Endocrine Connections, February 2022; 11(2), e210581

2. Sahare P, Ruiz-Manriquez LM, Anguiano B, Banerjee A, Pathak S, Duttaroy AK, Luna-Bárcenas G, Paul S, Recent advances in nanomedicine for the diagnosis and therapy of thyroid disorders, 3 Biotech, November 2025; 3(67), 1-20 online

3. Montes de Oca, C.; Álvarez, L.; Aceves, C.; Anguiano, B, Molecular Iodine Induces Anti- and Pro-Neoplastic Effects in Prostate Cancer Models, International Journal in Molecular Sciences, August 2025; 26(16), 1-18 online

4. Mendieta I, Leon-Pichardo J, Orizaga-Osti G, Juvera-Avalos ER, Rangel-Chavez U, Delgado-Gonzalez E, Anguiano B, Aceves C, Molecular Iodine Exhibited Differential Antiproliferative Actions in Progenitor and Stem Populations from Chemoresistant Cancer , International Journal in Molecular Sciences, April 2025; 26(9), 1-16 online

5. Rodríguez-Castelán J, Delgado-González E, Sánchez-Tapia M, Anguiano B, Torres N, Aceves C, Preventive and therapeutic effects of molecular iodine in a model of diabetes mellitus induced by streptozotocin, Journal of Nutritional Biochemistry, October 2024; 16(135), 109783.

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Publicaciones

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1. Anguiano B (autor responsable), Montes de Oca C, Delgado-González E, Aceves C. , Prostate Gland a Target Organ of Thyroid Hormones Action; Advances and Controversies. , Endocrine Connections, February 2022; 11(2), e210581

2. Sahare P, Ruiz-Manriquez LM, Anguiano B, Banerjee A, Pathak S, Duttaroy AK, Luna-Bárcenas G, Paul S, Recent advances in nanomedicine for the diagnosis and therapy of thyroid disorders, 3 Biotech, November 2025; 3(67), 1-20 online

3. Montes de Oca, C.; Álvarez, L.; Aceves, C.; Anguiano, B, Molecular Iodine Induces Anti- and Pro-Neoplastic Effects in Prostate Cancer Models, International Journal in Molecular Sciences, August 2025; 26(16), 1-18 online

4. Mendieta I, Leon-Pichardo J, Orizaga-Osti G, Juvera-Avalos ER, Rangel-Chavez U, Delgado-Gonzalez E, Anguiano B, Aceves C, Molecular Iodine Exhibited Differential Antiproliferative Actions in Progenitor and Stem Populations from Chemoresistant Cancer , International Journal in Molecular Sciences, April 2025; 26(9), 1-16 online

5. Rodríguez-Castelán J, Delgado-González E, Sánchez-Tapia M, Anguiano B, Torres N, Aceves C, Preventive and therapeutic effects of molecular iodine in a model of diabetes mellitus induced by streptozotocin, Journal of Nutritional Biochemistry, October 2024; 16(135), 109783.

6. Delgado-González E, De los Ríos-Arellano E, Anguiano B, Aceves C, Molecular Iodine Improves the Efficacy and Reduces the Side Effects of Metronomic Cyclophosphamide Treatment Against Mammary Cancer Progression, International Journal of Molecular Sciences, August 2024; 25(16), 8822

7. Anguiano B (Autora de correspondencia), Álvarez L, Delgado-González E, Ortiz-Martínez Z, Montes de Oca C, Morales G, Aceves C. , Protective effects of iodine on rat prostate inflammation induced by sex hormones and on the DU145 prostate cancer cell line treated with TNF. , Molecular Celular Endocrinology, November 2023; 572(111957)

8. Rodríguez-Castelán J, Delgado-González E, Rodríguez-Benítez E, Castelán F, Cuevas-Romero E, Anguiano B, Jeziorski MC, Aceves C., Preventive Effect of Molecular Iodine in Pancreatic Disorders from Hypothyroid Rabbits. , International Journal of Molecular Sciences, November 2023; 24(19), 14903

9. Rodríguez-Castelán J, Delgado-González E, Varela-Floriano V, Anguiano B, Aceves C. Molecular , Molecular Iodine Supplement Prevents Streptozotocin-Induced Pancreatic Alterations in Mice. , Nutrients, February 2022; 14(3), 715

10. Cuenca-Micó O, Delgado-González E, Anguiano B, Vaca-Paniagua F, Medina-Rivera A, Rodríguez-Dorantes M, Aceves C, Effects of Molecular Iodine/Chemotherapy in the Immune Component of Breast Cancer Tumoral Microenvironment, Biomolecules, November 2021; 11(10), 1501

11. Ruiz-Sánchez E, López-Ramírez AM, Ruiz-Chow A, Calvillo M, Reséndiz-Albor AA, Anguiano B and Rojas P , Variability in Behavioral Phenotypes after Forced Swimming-Induced Stress in Rats Is Associated with Expression of the Glucocorticoid Receptor, Nurr1, and IL-1in the Hippocampus, International Journal of Molecular Sciences, November 2021; 22(12700.)

12. Winniberg Álvarez-León, Irasema Mendieta, Evangelina Delgado-González, Brenda Anguiano, Carmen Aceves , Molecular Iodine/Cyclophosphamide Synergism on Chemoresistant Neuroblastoma Models, International Journal of Molecular Sciences, August 2021; 22(16), 8936.

13. Aceves C, Mendieta I, Anguiano B, Delgado-González E. , Molecular Iodine Has Extrathyroidal Effects as an Antioxidant, Differentiator, and Immunomodulator., International Journal Of Molecular Sciences, January 2021; 22(3), 1228

14. Sánchez-Tusie A, Montes de Oca C, Rodríguez-Castelán J, Delgado-González E, Ortiz Z, Álvarez L, Zarco C, Aceves C, Anguiano B. , A rise in T3/T4 ratio reduces the growth of prostate tumors in a murine model. , J Endocrinol, December 2020; 247(3), 225-238

15. Mendieta I, Rodríguez-Gómez G, Rueda-Zarazúa B, Rodríguez-Castelán J, Álvarez-León W, Delgado-González E, Anguiano B, Vázquez-Martínez O, Díaz-Muñoz M, Aceves C. , Molecular iodine synergized and sensitized neuroblastoma cells to the antineoplastic effect of ATRA, Endocrine-Related Cancer, March 2020; 27(12), 699-710 online

16. Mirle Peña, Evangelina Delgado-Gonzalez, Luz M. López-Marín, Blanca E. Millán-Chiu, Francisco Fernández, Julia Rodriguez-Castelan, Carolina Muñoz-Torres, Giovana Carrasco, Brenda Anguiano, Achim M. Loske, Carmen Aceves. Ultrasound in Medicine and Biology., Shock Wave Application Synergizes the Antineoplastic Effect of Molecular Iodine Supplement in Breast Cancer Xenografts, Ultrasound in Medicine and Biology, March 2020; 46(3), 649-659

17. Aura Moreno-Vega, Laura Vega-Riveroll, Tonatiuh Ayala, Guillermo Peralta, Jose Miguel Torres-Martel, Joel Rojas, Perla Mondragon, Adriana Dominguez, Rodrigo De Obaldia, Carlos Avecilla-Guerrero, Brenda Anguiano, Evangelina Delgado-Gonzalez, Xochitl Zambrano-Estrada, Olga Cuenca-Mico, Alfredo Varela, and Carmen Aceves. (2019). Adjuvant Effect of . Nutrients. 11, 1623 (4.1) , Molecular Iodine in Conventional Chemotherapy for Breast Cancer. Randomized Pilot Study, Nutrients, July 2019; 11(7), 1623

18. Mendieta I, Nuñez-Anita E, Nava-Villalba M, Zambrano-Estrada X, Delgado-Gonzalez, E; Anguiano B, Aceves C, Molecular iodine exerts antineoplastic effects by re-differentiation tumoral cells and activation of immune response in mammary cancer xenografts, BMC CAncer, April 2019; (19), 261

19. Quintero-García M, Delgado-González-E, Sánchez-Tusie A, Vázquez M, Aceves C, Anguiano B , Iodine prevents testosterone-induced oxidative stress in a model of rat prostatic hiperplasia, Free Radical Biology & Medicine, November 2018; 115, 298-308

20. Zambrano-Estrada X, Landaverde-Quiroz B, Dueñas-Bocanegra AA, De Paz-Campos MA, Hernández-Alberto G, Solorio-Perusquia B, Trejo-Mandujano M, Pérez-Guerrero L, Delgado-González E, Anguiano B, Aceves C., Molecular iodine/doxorubicin neoadjuvant treatment impair invasive capacity and attenuate side effect in canine mammary cancer., BMC Veterinary Research, November 2018; 14(1), 87

21. Delgado-González E, Aceves C, Anguiano B (autor de correspondencia), Triiodothyronine attenuates prostate cancer progression mediated by beta-adrenergic stimulation, Molecular Medicine, November 2016; 22, 1-11

22. Delgado G, Muñoz-Torres C, Orozco-Esquivel T, Anguiano B and Aceves C., Total iodine quantification in fluids and tissues from iodine- or iodide-supplemented rats by ion chromatography following microwave-assisted digestion, Thyroid, November 2015; 25(3), 352-360

23. Rodríguez A, Alva-Sánchez C, Villanueva I, Anguiano B, Aceves C, Pacheco-Rosado J (2014). , The NMDA Receptor Antagonist MK-801 Abolishes the increase in both p53 AND Bax/Bcl2 index induced by adult-onset hypothyroidism in rat. , Acta Neurobiologiae Experimentalis, November 2014; 74(1), 111-117 online

24. Ayala-Moreno R, Racotta R, Anguiano B, Aceves C, Quevedo L , Perinatal undernutrition programs thyroid function in the adult offspring rat, British Journal of Nutrition, December 2013; 110(12), 2207-2215

25. Olvera-Caltzontzin P, Delgado G, Aceves C, Anguiano B , Iodine uptake and prostate cancer in the TRAMP mouse model, Molecular Medicine, November 2013; 19, 409-416

26. Aceves C, Anguiano B, Delgado G, The extrathyronine actions of iodine. Antioxidant, apoptotic, and differentiation factor in iodine-uptake tissues, Thyroid, August 2013; 8, 938-946

27. Alfaro Y, Delgado G, Cárabez A, Anguiano B, Aceves C, Iodine and anthracyclines: a good combination for mammary cancer treatment. Antineoplastic adjuvancy, chemoresistance inhibition and cardioprotection, Molecular Cancer, May 2013; 12(45), 1-11

28. Aranda N, Sosa S, Delgado G, Aceves C, Anguiano B , Uptake and Apoptotic Effects of Iodine in Differentiated and Undifferentiated Human Prostate Cancer Cell Lines, Prostate, January 2013; 73(1), 31-41

29. Lopez G, Lona Díaz V, Anguiano Serrano B, Luna Muñoz M, Morato Cartagena T, Romero Ramírez CM, Blood levels of cortisol and glucocorticoid receptors in liver and placenta of goats at different stages of gestation, Veterinaria Mexico, December 2012; 43(3), 213-223

30. Alvarez-Salas E., Aceves C., Anguiano B., Uribe RM., Sánchez E., de Gortari P, Food Restricted and Anorexic Rats Present Differential TRH Expression in Anterior and Caudal PVN. Role of Type 2 Deiodinase and Pyroglutamyl Aminopeptidase, Endocrinology, August 2012; 153(8), 4067–4076

31. Anguiano B, Aceves C, Iodine in mammary and prostate pathologies, Current Chemical Biology, September 2011; 5(3), 177-182 online

32. Soriano O, Delgado G, Anguiano B, Petrosyan P, Molina-Servín ED, Gonsebatt ME, Aceves C , Antineoplastic effect of iodine and iodide in DMBA-induced mammary tumors. Association between lactoperoxidase and estrogen-adduct production, Endocrine-Related Cancer, July 2011; 18(4), 529-539 online

33. Delgado-Gonzalez E, Aceves C, Anguiano B, The prostatic post-ejaculatory increase of triiodothyronine (T3) depends on sympathetic innervation in the rat. , Biology Of Reproduction, January 2011; 84(1), 118-123

34. López-Juárez A, Delgado G, Aceves C, Anguiano B , Type 1 deiodinase activity and generation of triiodothyronine (T3) in prostate of sexually active rats, Prostate, July 2009; 69(15), 1651-1659 online

35. Aceves C, García-Solís P, Arroyo-Helguera O, Vega-Riveroll L, Delgado G, Anguiano B, Antineoplastic effect of iodine in mammary cancer. Participation of 6-iodolactone (6-IL) and peroxisome proliferators-activated receptors (PPAR), Molecular Cancer, June 2009; 8, 33-41 online

36. Alva-Sánchez, C, Sánchez-Huerta K, Arroyo-Helguera O, Anguiano B, Aceves C, Pacheco-Rosado J, The maintenance of hippocampal pyramidal neuron populations is dependent on the modulation of specific cell cycle regulators by thyroid hormones., Brain Research, May 2009; 1271, 27-35

37. Alva-Sánchez C, Becerril A, Anguiano B, Aceves C, Pacheco-Rosado J , Participation of NMDA-glutamatergic receptors in hippocampal neuronal damage caused by adult-onset hypothyroidism, Neuroscience Letters, April 2009; 453(3), 178-181

38. Anguiano B, Aranda N, Delgado G, Aceves C, Epididymis express the highest 5´deiodinase activity in the male reproductive system: kinetic characterization, distribution, and hormonal regulation., Endocrinology, August 2008; 149(8), 4209-4217 online

39. Anguiano B, García-Solís P, Delgado G, Aceves C, Uptake and gene expression of antitumoral mammary doses of iodine in thyroid and mammary gland. Evidence of no harmful effects in chronic administration. , Thyroid, September 2007; 17(9), 851-859 online

40. Luna-Estrada A., Vera-Ávila H., Mora-Izaguirre O., Anguiano B., Vásquez-Peláez C., Shimada-Miyasaka A., Effect of the pre-mating nutritional status in red deer (Cervus Elaphus scoticus) hinfds, on their subsequent offspring´s sex ratio , Small Ruminant Research, September 2006; 65(1-2), 154-160 online

41. Anguiano B., López A., Delgado G., Romero C., Aceves C., Deiodinase type 1 is expressed in prostate of pubescent rats and is modulated by prolactin and sex hormones. , Journal Of Endocrinology, August 2006; 190(2), 363-371 online

42. Arroyo-Helguera O., Anguiano B., Delgado G., Aceves C., Uptake and antiproliferative effect of molecular iodine in the MCF-7 breast cancer cell line., Endocrine-Related Cancer, January 2006; 13(4), 1147-1158 online

43. García-Solís P., Alfaro Y., Anguiano B., Delgado G., Guzmán R.C., Nandi S., Díaz-Muñoz M, Vázquez-Martínez O and Aceves C., Inhibition of induced-MNU mammary carcinogenesis by molecular iodine (I2) but not by iodide (I-) treatment. Evidence that I2 prevent cancer promotion. , Molecular And Cellular Endocrinology, May 2005; 236(1-2), 49-57 online

44. Aceves C., Anguiano B., Delgado G., Is Iodine a gatekeeper of the integrity of the mammary gland?. Articulo de revisión por invitación., Journal Of Mammary Gland Biology And Neoplasia, January 2005; 10(2), 189-196 online

45. Anguiano B, Rojas-Huidobro R, Delgado G, Aceves C, Has the mammary gland a protective mechanism against overexposure to triiodothyronine during the peripartum period? The prolactin pulse down-regulates mammary type I deiodinase responsiveness to norepinephrine. , J Endocrinol, November 2004; 183(2), 267-277 online

46. Anguiano B., Valverde-R.C., Cold induced increment in rat adrenal gland type II deiodinase (AGD2) is corticosterone dependent. , Endocrine, January 2001; 15(0), 87-91

47. Anguiano B., Quintanar A., Luna M., Navarro L., Ramírez del Angel A., Pacheco P., et al., NEUROENDOCRINE REGULATION OF ADRENAL GLAND AND HYPOTHALAMUS 5'DEIODINASE ACTIVITY. II. EFFECTS OF SPLANCHNICTOMY AND HYPOPHYSECTOMY, Endocrinology, January 1995; 136(0), 3346-3352 online

48. Luna M., Anguiano B., Valverde-R.C., ADRENAL GLAND 5' DEIODINASE ACTIVITY (AG-5'D). KINETIC CHARACTERIZATION AND FRACTIONAL TURNOVER RATE (FTR). , Endocrine, January 1995; 3(0), 361-366

49. Acuña D, Aceves C, Anguiano B, Meza G, Vestibular site of action of hypothyroidism in the pigmented rat., Brain Research, October 1990; 536(0), 133-138

50. Anguiano B., Aceves C., Navarro L., Ramirez del Angel A., Luna M., Perera G., Valverde-R C., Neuroendocrine regulation of adrenal 5'monodeiodination during acute cold exposure in the rat. , Endocrinology, October 1990; 128(0), 504-508 online

Most Recent Advised Theses

1. Carlos Fernando Montes de Oca Magallón (estudiante), Efectos del yodo y PPARG en la diferenciación neuroendócrina en modelos de cáncer de próstata resistentes a la castración. , Modalidad: Tesis, Doctorado en Ciencias Biomédicas (UNAM), Doctorado, Insituto de Neurobiología, Universidad Nacional Autónoma de México, Fecha de presentación de examen: 2025-12-09, Anguiano Serrano Rocío Brenda (Director)

2. Sara Reséndiz Argaíz (estudiante), Efectos de las hormonas tiroideas y yodo en el contenido de zinc y metabolismo lipídico en la próstata normal y tumoral, Modalidad: Tesina, Ingeniería en Biotecnología, Licenciatura, Química, Universidad Tecnologica de Corregidora , Fecha de presentación de examen: 2022-05-25, Anguiano Serrano Rocío Brenda (Director)

3. Luis Adán Martínez Avila (estudiante), Influencia del yodo en la expresión de genes relacionados con la señalización de andrógenos y el factor antioxidante Nrf2 en un modelo de inflamación prostática inducida por estrógenos, Modalidad: Tesis, Ingenieria Bioquímica, Licenciatura, Tecnologico Nacional en Celaya, Instituto Tecnologico de Celaya, Fecha de presentación de examen: 2021-01-29, Anguiano Serrano Rocío Brenda (Director)

4. Emma Patiño Ojeda (estudiante), Efectos del yodo en la expresión de genes relacionados con la vía de señalización de andrógenos y estrógenos en la próstata normal y tumoral murina, Modalidad: Tesis, Ingeniería Bioquímica, Licenciatura, Bioquímica, Instituto Tecnologico de Celaya, Fecha de presentación de examen: 2019-11-07, Anguiano Serrano Rocío Brenda (Director)

5. Neftali Ammi Márquez Santiago (estudiante), Apoyo técnico en el análisis de los efectos del yodo en patologías prosta´ticas, Modalidad: Tesis, Química: Tecnología Farmaceútica, Técnico, Química, Universidad Tecgnológica de San Juan del Río, Fecha de presentación de examen: 2019-09-20, Anguiano Serrano Rocío Brenda (Director)